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What is the half life of pravastatin? Plasma elimination half - life of oral pravastatin is 1.5 to 2 hours. After intravenous administration, 47% of the dose is eliminated by renal excretion and 53% by biliary excretion and biotransformation.
Why are statins bad? While statins are highly effective and safe for most people, they have been linked to muscle pain, digestive problems and mental fuzziness in some people who take them and may rarely cause liver damage.
What are the long term effects of simvastatin? Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins.
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