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Is phenothiazine a sedative? Phenothiazines. Promethazine, a phenothiazine derivative, is occasionally administered to control nausea and vomiting when opioids are used before anesthesia. In addition to its sedative properties, promethazine is an H 1 blocker and has antiemetic, antihistaminic, anti–motion sickness, and anticholinergic effects.
Does risperidone cause gynecomastia? Gynecomastia (breast enlargement) is a side effect of neuroleptic antipsychotic drugs, related to prolactin elevation caused by dopamine D2 receptor blockade (Richelson, 1996). The atypical antipsychotic risperidone is less likely to cause gynecomastia at low doses (Casey, 1996).
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